Last update 08 May 2025

KY-001

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(1S,2S,6S)-6-((S)-5-chloro-6-fluoro-2-phenyl-2-((S)-pyrrolidin-2-yl)-2,3-dihydrobenzofuran-4-yl)-7-fluoro-1-hydroxy-N,2-dimethyl-2,3-dihydro-1H-indene-5-carboxamide
Target
TEAD x YAP1
Action
inhibitors
Mechanism
TEAD inhibitors(TEA domain transcription factors inhibitors), YAP1 inhibitors(Yes1 associated transcriptional regulator inhibitors)
Therapeutic Areas
NeoplasmsRespiratory DiseasesOther Diseases
Active Indication
Advanced Malignant Solid NeoplasmMalignant Pleural Mesothelioma
Inactive Indication-
Originator Organization
Kygent Therapeutics (Shanghai) Co., Ltd.
Active Organization
Kygent Therapeutics (Shanghai) Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseIND Approval
First Approval Date-
RegulationOrphan Drug (United States)
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Related

100 Clinical Results associated with KY-001
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100 Translational Medicine associated with KY-001
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100 Patents (Medical) associated with KY-001
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100 Deals associated with KY-001
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmIND Approval
China
Kygent Therapeutics (Shanghai) Co., Ltd.
30 Jul 2024
Malignant Pleural MesotheliomaIND Approval
China
Kygent Therapeutics (Shanghai) Co., Ltd.
30 Jul 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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