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Clinical Trials associated with Rituximab biosimilar (Chia-tai Tianqing) / Not yet recruitingPhase 2IIT A Prospective, Single-Arm, Phase II Clinical Study of RP Regimen in Previously Untreated Indolent B-Cell Lymphoma
TQB2825注射液联合免疫化疗在弥漫大B细胞淋巴瘤受试者中的Ib/II期临床试验
[Translation] Phase Ib/II clinical trial of TQB2825 injection combined with immunochemotherapy in subjects with diffuse large B-cell lymphoma
主要目的:
评估TQB2825联合免疫化疗的剂量限制性毒性(DLT)、最大耐受剂量(MTD)和II期推荐剂量(RP2D)
次要目的:
通过评估ORR、CR率、PFS、DOR和OS等评估TQB2825联合免疫化疗在弥漫大B细胞淋巴瘤受试者中的初步有效性
评价TQB2825联合免疫化疗在弥漫大B细胞淋巴瘤受试者中的安全性
探索性目的:
评价基因突变和ctDNA与其他指标的相关性。
[Translation] Primary purpose:
To evaluate the dose-limiting toxicity (DLT), maximum tolerated dose (MTD) and phase II recommended dose (RP2D) of TQB2825 combined with immunochemotherapy
Secondary purpose:
To evaluate the preliminary efficacy of TQB2825 combined with immunochemotherapy in subjects with diffuse large B-cell lymphoma by evaluating ORR, CR rate, PFS, DOR and OS
To evaluate the safety of TQB2825 combined with immunochemotherapy in subjects with diffuse large B-cell lymphoma
Exploratory purpose:
To evaluate the correlation between gene mutations and ctDNA and other indicators.
TQB2825注射液联合化疗在复发/难治性弥漫大B细胞淋巴瘤受试者中的II期临床试验
[Translation] Phase II clinical trial of TQB2825 injection combined with chemotherapy in subjects with relapsed/refractory diffuse large B-cell lymphoma
主要目的:评估TQB2825联合化疗在复发/难治性弥漫大B细胞淋巴瘤受试者中的初步有效性。次要目的:通过评估ORR、PFS、DOR、TTR和OS等评估TQB2825联合化疗在复发/难治性弥漫大B细胞淋巴瘤受试者中的初步有效性。探索性目的:评价TQB2825联合化疗时在复发/难治性弥漫大B细胞淋巴瘤受试者中药代动力学、免疫原性生物标志物与疗效的相关性。
[Translation] Primary objective: To evaluate the preliminary efficacy of TQB2825 combined with chemotherapy in subjects with relapsed/refractory diffuse large B-cell lymphoma. Secondary objective: To evaluate the preliminary efficacy of TQB2825 combined with chemotherapy in subjects with relapsed/refractory diffuse large B-cell lymphoma by evaluating ORR, PFS, DOR, TTR and OS. Exploratory objective: To evaluate the correlation between pharmacokinetic and immunogenic biomarkers and efficacy of TQB2825 combined with chemotherapy in subjects with relapsed/refractory diffuse large B-cell lymphoma.
100 Clinical Results associated with Rituximab biosimilar (Chia-tai Tianqing)
100 Translational Medicine associated with Rituximab biosimilar (Chia-tai Tianqing)
100 Patents (Medical) associated with Rituximab biosimilar (Chia-tai Tianqing)
100 Deals associated with Rituximab biosimilar (Chia-tai Tianqing)