Last update 28 Feb 2026

ZB-003

Overview

Basic Info

Drug Type
Fc fusion protein
Synonyms
XPRO9523, XPro9523, ZB 003
+ [1]
Target
CD80 x CD86
Action
inhibitors
Mechanism
CD80 inhibitors(Cluster of differentiation 80 inhibitors), CD86 inhibitors(Cluster of differentiation 86 inhibitors)
Therapeutic Areas
Immune System DiseasesSkin and Musculoskeletal Diseases
Active Indication
Rheumatoid ArthritisAutoimmune Diseases
Inactive Indication-
Originator Organization
Xencor, Inc.Xencor, Inc.
Active Organization
Xencor, Inc.Xencor, Inc.Zenas BioPharma LLC.Zenas BioPharma LLC.
Inactive Organization-
License Organization
Xencor, Inc.Xencor, Inc.Shanghai Zenas Biotechnology Co., Ltd.
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with ZB-003
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100 Translational Medicine associated with ZB-003
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100 Patents (Medical) associated with ZB-003
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100 Deals associated with ZB-003
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Autoimmune DiseasesPreclinical
United States
Zenas BioPharma LLC.Zenas BioPharma LLC.
23 Mar 2021
Rheumatoid ArthritisPreclinical
United States
Xencor, Inc.Xencor, Inc.
27 Oct 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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