Last update 01 Nov 2024

Entinostat/Erlotinib Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
EGFR x HDAC1 x HDAC2 x HDAC3
Mechanism
EGFR antagonists(Epidermal growth factor receptor erbB1 antagonists), HDAC1 inhibitors(Histone deacetylase 1 inhibitors), HDAC2 inhibitors(Histone deacetylase 2 inhibitors)
+ [1]
Therapeutic Areas
NeoplasmsRespiratory Diseases
Active Indication
Non-Small Cell Lung Cancer
Inactive Indication-
Originator Organization
Colorado State UniversityColorado State University
Active Organization
Colorado State UniversityColorado State University
Inactive Organization
Syndax Pharmaceuticals, Inc.Syndax Pharmaceuticals, Inc.
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC22H24ClN3O4
InChIKeyGTTBEUCJPZQMDZ-UHFFFAOYSA-N
CAS Registry183319-69-9
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Related

100 Clinical Results associated with Entinostat/Erlotinib Hydrochloride
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100 Translational Medicine associated with Entinostat/Erlotinib Hydrochloride
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100 Patents (Medical) associated with Entinostat/Erlotinib Hydrochloride
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100 Deals associated with Entinostat/Erlotinib Hydrochloride
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 2-
Colorado State UniversityColorado State University
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
WCLC2017
Not Applicable
Non-Small Cell Lung Cancer
Maintenance
11
(hrtqzoyjpe) = jdqjzssknz vnylpyiqzy (epuqihxrbk )
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-
17 Oct 2017
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Clinical Trial

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Approval

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Regulation

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