Last update 28 Jun 2025

LLP2A alendronate

Overview

Basic Info

Drug Type
Peptide drug conjugates
Synonyms-
Target
α4β1
Action
modulators
Mechanism
α4β1 modulators(Integrin alpha-4/beta-1 modulators)
Therapeutic Areas
Endocrinology and Metabolic DiseaseSkin and Musculoskeletal DiseasesOther Diseases
Active Indication-
Inactive Indication
OsteonecrosisOsteoporosis
Originator Organization
University of CaliforniaUniversity of California
Active Organization-
Inactive Organization
University of California, DavisUniversity of California, Davis
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC88H133N17O28P2S
InChIKeyFGRUYPCSKHMJMZ-RHHLPLLSSA-N
CAS Registry1363159-28-7
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Related

1
Clinical Trials associated with LLP2A alendronate
NCT03197623
/ CompletedPhase 1IIT
A Phase 1, Randomized, Double-Blind, Placebo-Controlled Single and Multiple Ascending Dose Study of the Safety and Tolerability of Intravenous LLP2A-Alendronate in Adult Men and Women With Osteopenia Secondary to Glucocorticoids
100 Clinical Results associated with LLP2A alendronate
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100 Translational Medicine associated with LLP2A alendronate
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100 Patents (Medical) associated with LLP2A alendronate
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100 Deals associated with LLP2A alendronate
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
OsteonecrosisPhase 1
United States
University of California, DavisUniversity of California, Davis
14 Oct 2016
OsteoporosisPhase 1
United States
University of California, DavisUniversity of California, Davis
14 Oct 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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