100 Clinical Results associated with Heterocycle-fused 1,4-benzoquinone(Korea Advanced Institute of Science and Technology)
100 Translational Medicine associated with Heterocycle-fused 1,4-benzoquinone(Korea Advanced Institute of Science and Technology)
100 Patents (Medical) associated with Heterocycle-fused 1,4-benzoquinone(Korea Advanced Institute of Science and Technology)
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Literatures (Medical) associated with Heterocycle-fused 1,4-benzoquinone(Korea Advanced Institute of Science and Technology)Leveraging heterocycle-fused 1,4-benzoquinone to design chemical modulators for both metal-free and metal-bound amyloid-β
Article
Author: Kim, Kyungmin ; Kim, Hakwon ; Lim, Mi Hee ; Yi, Yelim
We designed heterocycle-fused 1,4-benzoquinone (BQ) compounds against the amyloidogenesis of metal-free and metal-bound Aβ. They interact with metal ions and Aβ, redirecting the assembly of metal-free Aβ and metal–Aβ to form less toxic aggregates.
100 Deals associated with Heterocycle-fused 1,4-benzoquinone(Korea Advanced Institute of Science and Technology)