Delving into the Latest Updates on Malaria vaccine(National Institute of Allergy & Infectious Diseases) with Synapse

Overview

Basic Info

Drug Type

Recombinant vector vaccine, Prophylactic vaccine

Synonyms

Malaria vaccine

Target-

Mechanism

Immunostimulants

Therapeutic Areas

Infectious Diseases

Active Indication

Malaria

Inactive Indication-

Originator Organization

National Institute of Allergy & Infectious Diseases

Active Organization

Crucell Holdings, Inc.

Program for Appropriate Technology in HealthNational Institute of Allergy & Infectious Diseases

+ [1]

Inactive Organization-

Drug Highest PhasePhase 1

First Approval Date-

Regulation-

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The overall goal of this study is to assess the impact of RTS,S (malaria) vaccination and PBO nets on malaria infection and transmission, independently and how they interact when they are introduced together.
The specific objectives for the study are as follows:
1. To estimate the impact of PBO nets and RTS,S vaccine on Plasmodium infection prevalence and transmission, independently and how they interact when they are introduced together in Malawi (Phase 1).
2. To assess the feasibility of evaluating the impact of RTS,S vaccine and PBO nets independently in a larger scale future study.

Start Date04 Feb 2020

Sponsor / Collaborator

Michigan State University

[+3]

EUCTR2019-002872-14-GB / Unknown statusPhase 1/2IIT

A Phase I/IIa clinical trial to assess the safety, immunogenicity and efficacy of the blood-stage Plasmodium vivax malaria vaccine candidate PvDBPII in Matrix M1 in healthy adults living in the UK - VAC079: Safety and efficacy of the PvDBPII in Matrix M1 vaccine

Start Date12 Nov 2019

Sponsor / Collaborator-

100 Clinical Results associated with Malaria vaccine(National Institute of Allergy & Infectious Diseases)

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100 Translational Medicine associated with Malaria vaccine(National Institute of Allergy & Infectious Diseases)

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100 Patents (Medical) associated with Malaria vaccine(National Institute of Allergy & Infectious Diseases)

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141

Literatures (Medical) associated with Malaria vaccine(National Institute of Allergy & Infectious Diseases)

31 Dec 2024·Human Vaccines & Immunotherapeutics

A systematic review on malaria and dengue vaccines for the effective management of these mosquito borne diseases: Improving public health

Review

Author: Alanzi, Abeer ; Shrwani, Reem ; Albalawi, Reem ; Saad, Abrar ; Marghlani, Lujain ; Althobaiti, Khaled ; Alasmari, Saba ; Alsofiyani, Razan ; Al-Rowaili, Badria ; Al-Osaimi, Hind M ; Alhulaili, Zainab ; Alqarni, Rawan ; Kanan, Mohammed

Insect vector-borne diseases (VBDs) pose significant global health challenges, particularly in tropical and subtropical regions. The WHO has launched the "Global Vector Control Response (GVCR) 2017-2030" to address these diseases, emphasizing a comprehensive approach to vector control. This systematic review investigates the potential of malaria and dengue vaccines in controlling mosquito-borne VBDs, aiming to alleviate disease burdens and enhance public health. Following PRISMA 2020 guidelines, the review incorporated 39 new studies out of 934 identified records. It encompasses various studies assessing malaria and dengue vaccines, emphasizing the significance of vaccination as a preventive measure. The findings indicate variations in vaccine efficacy, duration of protection, and safety considerations for each disease, influencing public health strategies. The review underscores the urgent need for vaccines to combat the increasing burden of VBDs like malaria and dengue, advocating for ongoing research and investment in vaccine development.

01 Dec 2024·New Microbes and New Infections

Malaria vaccine - A solution to the endemic burden of malaria in the Democratic Republic of the Congo; a call for action

Article

Author: RUGENDABANGA, Excellent ; Biamba, Chrispin ; Mohamed Mousa, Hazem ; Jafar, Faizullah ; HANGI, Samson ; ONESIME, Jones ; Mohamed MOUSA, Hazem ; AKILIMALI, Aymar ; BIAMBA, Chrispin ; Onesime, Jones ; Moustafa BUDAIR, Mayar ; JAFAR, Faizullah ; KIHANDUKA, Elie ; Hangi, Samson ; Akilimali, Aymar ; Rugendabanga, Excellent ; Kihanduka, Elie ; Moustafa Budair, Mayar

01 Nov 2024·Travel Medicine and Infectious Disease

New Malaria vaccine a boon to Endemic regions - Doubling efficacy rates, at lower cost

Letter

Author: Feehan, Jack ; Lippmann, Steven ; Sah, Ranjit ; Mehta, Vini ; Mehta, Rachana ; Apostolopoulos, Vasso ; Kahlon, Amrit

100 Deals associated with Malaria vaccine(National Institute of Allergy & Infectious Diseases)

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External Link

KEGG	Wiki	ATC	Drug Bank
-	Malaria vaccine(National Institute of Allergy & Infectious Diseases)	-	-

R&D Status

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Malaria	Phase 1	-	Program for Appropriate Technology in Health	-
Malaria	Phase 1	-	National Institute of Allergy & Infectious Diseases	-
Malaria	Phase 1	-	Novavax, Inc.	-
Malaria	Phase 1	-	Crucell Holdings, Inc.	-