cf. preceding abstractsCHCl3, CCl4, CH2Cl2, and CHCl2CHCl2 completely eliminated the x-ray diffraction pattern of the rat sciatic nerve after a 5-hr. incubation, while CHCl:CHCl and CHCl:CCl2 produced these effects after 10-20 hrs.CH3CHClCH3, CH3CH2CH2Cl, CH3(CH2)2CH2Cl, CH3(CH2)3CH2Cl, CH3(CH2)4CH2Cl, Cl2CH(CH2)2CH3, Cl(CH2)4Cl, CH3(CH2)4CH3, and CH3(CH2)3CH3 all had a slow action, and the diffraction pattern remained moderately intense after a 24-hr. treatment of the nerve.The slow-acting hydrocarbons produced addnl. diffractions at 100 and 50 A., and CH3(CH2)3CH2Cl, CH3(CH2)3CH3, CH3(CH2)2CH2Cl, and CH3CH2CH2Cl produced a weakening of the 45 A. band; CH3(CH2)3CH2Cl and CH3(CH2)2CH2Cl eventually also weakened the 50 A. band, leaving only a weak diffraction in the 80-100 A. region.The size of the nonpolar solvent mol. is apparently the most important factor in the disorganization.No correlations were found between the speed of action and either the dipole moment or dielec. constant of the solvents.