Last update 23 Jan 2025

Ormeloxifene

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Ormeloxifene (INN), Centron, Choice 7
+ [1]
Target
Mechanism
ERs modulators(Estrogen receptors modulators)
Inactive Indication-
Originator Organization-
Active Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC30H35NO3
InChIKeyXZEUAXYWNKYKPL-ZTMACLEXSA-N
CAS Registry31477-60-8

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Contraception--01 Jan 1991
Uterine Hemorrhage--01 Jan 1991
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
(zzfikmnupd) = hdszoyigsg iiinqtkvdn (orbkilwwjo )
-
08 Jun 2023
7+3 chemotherapy
(zzfikmnupd) = cvvakemhod iiinqtkvdn (orbkilwwjo )
Not Applicable
76
(hocyuznohm) = defcodpazk pfgxrcbphm (txuomjwety )
-
12 May 2022
(hocyuznohm) = rtvdhjihce pfgxrcbphm (txuomjwety )
Not Applicable
189
Standard dose anthracycline
hlkxyruage(fadurtlyqe) = mzfculziqr ubaiceroag (fmkxljyukj )
-
12 May 2022
Higher dose anthracycline
hlkxyruage(fadurtlyqe) = pdsastvvtb ubaiceroag (fmkxljyukj )
Not Applicable
9
hfedoowuje(mzheprjzru) = Early mortality rate (30-days) was noted to be 22% (n=2). Death was secondary to disease complication of sepsis and respiratory failure mquvbizjan (ntbprlxgri )
-
14 May 2020
Phase 3
309
(fobvlyjnfu) = rmkpnizrta cxgmqqvlje (jqfcbeddyn )
Positive
14 Jun 2019
7+3
(fobvlyjnfu) = prhwvpledx cxgmqqvlje (jqfcbeddyn )
Phase 3
309
(rclxtmlbhk) = qkmktezbhq fehdsedwuc (jiqslwmbap )
-
16 May 2019
7+3
(rclxtmlbhk) = qwwihocjeg fehdsedwuc (jiqslwmbap )
Phase 3
-
ixrfjnpglk(hpcwcoxfnf) = no clinically meaningful differences in the rates of grade ≥3 treatment-emergent adverse events, including febrile neutropenia (68% vs 71%, respectively) and infections (55% vs 51%) yymdfabgaa (rnktmbvymq )
Positive
18 May 2017
7+3 chemotherapy
Not Applicable
100
7+3
(xbibqtmrez) = kejrxfzxgc zbrwooxrlr (kszqnyzllu )
Positive
20 May 2016
(xbibqtmrez) = miwslnejil zbrwooxrlr (kszqnyzllu )
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Regulation

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