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Last update 30 May 2025
GenSci128
Last update 30 May 2025
Overview
Basic Info
Drug Type Chemical drugs |
Synonyms GenSci128 |
Target |
Action activators |
Mechanism p53 Y220C activators(Cellular Tumor Antigen p53 Y220C activators) |
Therapeutic Areas |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
2
Clinical Trials associated with GenSci128NCT06908434
A Phase I, Multicenter, Multinational, Open-label, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of GenSci128 Tablet in Patients With Locally Advanced or Metastatic Solid Tumors Harboring a TP53 Y220C Mutation
CTR20251255
一项在携带TP53 Y220C突变的局部晚期或转移性实体瘤患者中评估GenSci128片的安全性、耐受性、药代动力学特征和有效性的国际多中心、开放标签、首次人体I期研究
[Translation] An international, multicenter, open-label, first-in-human Phase I study evaluating the safety, tolerability, pharmacokinetic characteristics, and efficacy of GenSci128 tablets in patients with locally advanced or metastatic solid tumors harboring TP53 Y220C mutations
100 Clinical Results associated with GenSci128
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100 Translational Medicine associated with GenSci128
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100 Patents (Medical) associated with GenSci128
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100 Deals associated with GenSci128
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | China | 01 Apr 2025 | |
| p53 Y220C mutation Solid Tumors | Phase 1 | China | 01 Apr 2025 |
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