Last update 21 Nov 2024

Hydrocortisone/Fradiomycin Sulfate/Dibucaine Hydrochloride/Esculoside

Last update 21 Nov 2024

Overview

R&D Status

Clinical Result

Translational Medicine

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

ネオマイシン硫酸塩/酢酸ヒドロコルチゾン/塩酸ジフェンヒドラミン, 氢化可的松/硫酸新霉素/盐酸辛可卡因/七叶苷, 硫酸ネオマイシン/酢酸ヒドロコルチゾン/塩酸ジフェンヒドラミン

+ [6]

Target-

Mechanism-

Therapeutic Areas

Cardiovascular DiseasesDigestive System Disorders

Active Indication

Fissure in AnoHemorrhoids

Inactive Indication-

Originator Organization

EA Pharma Co., Ltd.

Active Organization

EA Pharma Co., Ltd.J-DOLPH Pharmaceutical Co., Ltd.

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date

JP (11 Mar 1966),

Fissure in AnoHemorrhoids

Regulation-

Structure

Molecular FormulaC21H30O5

InChIKeyJYGXADMDTFJGBT-VWUMJDOOSA-N

CAS Registry50-23-7

View All Structures (3)

100 Clinical Results associated with Hydrocortisone/Fradiomycin Sulfate/Dibucaine Hydrochloride/Esculoside

100 Translational Medicine associated with Hydrocortisone/Fradiomycin Sulfate/Dibucaine Hydrochloride/Esculoside

100 Patents (Medical) associated with Hydrocortisone/Fradiomycin Sulfate/Dibucaine Hydrochloride/Esculoside

Literatures (Medical) associated with Hydrocortisone/Fradiomycin Sulfate/Dibucaine Hydrochloride/Esculoside

01 Jul 2005·The Southeast Asian journal of tropical medicine and public healthQ4 · MEDICINE

Prescription pattern for treatment of hemorrhoids under the universal coverage policy of Thailand.

Q4 · MEDICINE

Article

Author: Laosee, Orapin C ; Sitthi-amorn, Chitr ; Pathanapornpandh, Nopporn ; Khiewyoo, Jiraporn ; Dulyavoranun, Namthip ; Somrongthong, Ratana

The Universal Coverage Policy (UCP) or "30 Baht Scheme" was launched in Thailand in 2001. The policy caused a cutback in the budgets of all public hospitals and health service centers. Traditional medicine was then viewed as an alternative to save costs. This study examines whether this had any influence on hemorrhoid treatment prescription patterns, ratio of traditional/modern medicine, or the cost of hemorrhoid treatment after the UCP was implemented at a community hospital. The traditional medicine prescribed was Petch Sang Kart and the modern alternative was Proctosedyl. All hemorrhoid prescriptions at a community hospital from October 2000 to January 2003 were surveyed. Segmented Regression Analysis was applied to evaluate prescription trends, the ratios between the types of medicine, and the hemorrhoid treatment cost. A total of 256 prescriptions were analyzed. The average number of traditional medicine prescriptions per month were more than modern medicine (41 versus 16). During the study period, the trend of modern medicine use and the treatment cost was decreased (p < 0.01). The ratio of traditional/modern medicine increased 0.2 times (p = 0.02).

01 May 2001·Australasian Journal of DermatologyQ4 · MEDICINE

CASE REPORT Allergic contact dermatitis to cinchocaine

Q4 · MEDICINE

Article

Author: Christopher R Kearney ; John Fewings

SUMMARYA case of allergic contact dermatitis to cinchocaine is presented to highlight the confusion regarding the classification of, and cross‐reactivity between, topical anaesthetic agents and the inadequacy of the use of benzocaine as a single screening agent for topical anaesthetic contact allergy. Our patient presented with a 10‐day history of acute perianal dermatitis. Allergic contact dermatitis to Proctosedyl® ointment, which was applied for 3 weeks prior, was suspected. On patch testing, he reacted to cinchocaine, a constituent of Proctosedyl® ointment, and to the actual product, but had no reaction to benzocaine or lignocaine.

01 Nov 1998·Contact DermatitisQ2 · MEDICINE

Allergic contact dermatitis from dibucaine in Proctosedyl® ointment without cross‐sensitivity

Q2 · MEDICINE

Article

Author: Lee, A Y

100 Deals associated with Hydrocortisone/Fradiomycin Sulfate/Dibucaine Hydrochloride/Esculoside

R&D Status

10 top approved records.

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Indication	Country/Location	Organization	Date
Fissure in Ano	JP	EA Pharma Co., Ltd.	11 Mar 1966
Hemorrhoids	JP	EA Pharma Co., Ltd.	11 Mar 1966

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Hydrocortisone/Fradiomycin Sulfate/Dibucaine Hydrochloride/Esculoside

Overview

Basic Info

Structure

Related

R&D Status

Clinical Result

Translational Medicine

Deal

Core Patent

Clinical Trial

Approval

Regulation