Last update 13 Dec 2025

Monoclonal antibody anti-anb3 integrin(NCI)

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms-
Target
αvβ3
Action
antagonists
Mechanism
αvβ3 antagonists(Integrin alpha-V/beta-3 antagonists)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Advanced Malignant Solid Neoplasm
Originator Organization
National Cancer InstituteNational Cancer Institute
Active Organization-
Inactive Organization
Barbara Ann Karmanos Cancer InstituteBarbara Ann Karmanos Cancer Institute
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Monoclonal antibody anti-anb3 integrin(NCI)
NCT00052403
/ WithdrawnPhase 1IIT
Phase I Study of Monoclonal Antibody Anti-Anb3 Integrin in Patients With Advanced Solid Tumors
100 Clinical Results associated with Monoclonal antibody anti-anb3 integrin(NCI)
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100 Translational Medicine associated with Monoclonal antibody anti-anb3 integrin(NCI)
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100 Patents (Medical) associated with Monoclonal antibody anti-anb3 integrin(NCI)
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100 Deals associated with Monoclonal antibody anti-anb3 integrin(NCI)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1-
Barbara Ann Karmanos Cancer InstituteBarbara Ann Karmanos Cancer Institute
01 Feb 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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