Last update 25 Oct 2025

KRASG12V (Pramomolecular)

Overview

Basic Info

Drug Type
siRNA
Synonyms
Targeting KRAS G12V siRNA (Pramomolecular)
Target
KRAS G12V
Action
inhibitors
Mechanism
KRAS G12V inhibitors(GTPase KRas G12V inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [1]
Active Indication
Colorectal CancerNon-Small Cell Lung CancerPancreatic Ductal Adenocarcinoma
Inactive Indication-
Originator Organization
Pramomolecular GmbHPramomolecular GmbH
Active Organization
Pramomolecular GmbHPramomolecular GmbH
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

1
Clinical Trials associated with KRASG12V (Pramomolecular)
ChiCTR2100054460
/ RecruitingEarly Phase 1IIT
A clinical trial study for evaluating the efficacy of KRAS-mutated antigen-specific TCR T cell therapy for advanced pancreatic cancer
100 Clinical Results associated with KRASG12V (Pramomolecular)
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100 Translational Medicine associated with KRASG12V (Pramomolecular)
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100 Patents (Medical) associated with KRASG12V (Pramomolecular)
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100 Deals associated with KRASG12V (Pramomolecular)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Colorectal CancerPreclinical
Germany
Pramomolecular GmbHPramomolecular GmbH
08 Jun 2024
Non-Small Cell Lung CancerPreclinical
Germany
Pramomolecular GmbHPramomolecular GmbH
08 Jun 2024
Pancreatic Ductal AdenocarcinomaPreclinical
Germany
Pramomolecular GmbHPramomolecular GmbH
08 Jun 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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