Last update 21 Nov 2024

MDX-1342

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
Target
CD19
Mechanism
CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors)
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication-
Inactive Indication
CD19 Positive B-Cell Chronic Lymphocytic LeukemiaRheumatoid Arthritis
Originator Organization
Medarex, Inc.Medarex, Inc.
Active Organization-
Inactive Organization
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with MDX-1342
NCT00593944 / CompletedPhase 1
A Phase 1, Open-Label, Multiple-Dose, Dose-Escalation Study of MDX-1342 in Patients With CD19-Positive Refractory/Relapsed Chronic Lymphocytic Leukemia
NCT00639834 / CompletedPhase 1
A Phase 1, Multicenter, Single-dose, Dose-escalation, Safety and Tolerability Study of MDX-1342 (Anti-CD19 Human Monoclonal Antibody) in Combination With Methotrexate in Subjects With Active Rheumatoid Arthritis
100 Clinical Results associated with MDX-1342
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100 Translational Medicine associated with MDX-1342
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100 Patents (Medical) associated with MDX-1342
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1
Literatures (Medical) associated with MDX-1342
01 Feb 2010Cancer Immunology, ImmunotherapyQ2 · MEDICINE
A nonfucosylated human antibody to CD19 with potent B-cell depletive activity for therapy of B-cell malignancies
Q2 · MEDICINE
100 Deals associated with MDX-1342
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
CD19 Positive B-Cell Chronic Lymphocytic LeukemiaPhase 1
US
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
01 Aug 2008
Rheumatoid ArthritisPhase 1
US
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
01 Feb 2008
Rheumatoid ArthritisPhase 1
UA
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
01 Feb 2008
Rheumatoid ArthritisPhase 1
DE
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
01 Feb 2008
Rheumatoid ArthritisPhase 1
HU
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
01 Feb 2008
Rheumatoid ArthritisPhase 1
GB
Bristol Myers Squibb Co.Bristol Myers Squibb Co.
01 Feb 2008
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Clinical Result

Indication
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Evaluation
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Approval

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Regulation

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