Last update 21 Nov 2024
SIM-0508
Last update 21 Nov 2024
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms |
Target |
Mechanism POLQ inhibitors(DNA polymerase theta inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
2
Clinical Trials associated with SIM-0508评价SIM0508单药治疗及联合治疗在局部晚期/转移性实体瘤成人受试者的安全性、耐受性、药代动力学和初步抗肿瘤活性的首次人体、开放性、多中心I期研究
[Translation] A first-in-human, open-label, multicenter Phase I study to evaluate the safety, tolerability, pharmacokinetics, and preliminary anti-tumor activity of SIM0508 as monotherapy and in combination therapy in adult subjects with locally advanced/metastatic solid tumors
A Phase I, First-in-Human, Multicenter Study to Investigate the Safety, Tolerability, Pharmacokinetics and Preliminary Antitumor Activity of SIM0508 Monotherapy and Combination Therapy in Adult Participants With Locally Advanced/Metastatic Solid Tumors
100 Clinical Results associated with SIM-0508
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100 Translational Medicine associated with SIM-0508
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100 Patents (Medical) associated with SIM-0508
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100 Deals associated with SIM-0508
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced Malignant Solid Neoplasm | Phase 1 | CN | 04 Nov 2024 | |
| Solid tumor | IND Approval | US | 29 Aug 2024 | |
| Locally Advanced Malignant Solid Neoplasm | IND Approval | CN | 22 Aug 2024 | |
| Metastatic Solid Tumor | IND Approval | CN | 22 Aug 2024 |
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