Last update 25 Jan 2025

JY-231

Overview

Basic Info

Drug Type
Gene therapy
Synonyms
JY 231, JY231
Target
CD19
Mechanism
CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors), Cell replacements
Therapeutic Areas
Immune System DiseasesSkin and Musculoskeletal DiseasesNeoplasms+ [1]
Active Indication
Systemic Lupus ErythematosusRefractory B Acute Lymphoblastic LeukemiaCD19 positive B-Cell Lymphoma
Inactive Indication-
Originator Organization
Guangdong Provincial People's Hospital
Active Organization
920th Hospital of Joint Logistics Support Force of People's Liberation Army of ChinaGuangdong Provincial People's Hospital
Inactive Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

7
Clinical Trials associated with JY-231
NCT06689917
/ Not yet recruitingNot ApplicableIIT
An Early Exploratory Clinical Study of the Safety, Tolerability and Preliminary Efficacy of JY231 Injection in the Treatment of Relapsed or Refractory B-cell Lymphoma/Leukaemia
NCT06675422
/ RecruitingPhase 1/2IIT
JY231 Injection for the Treatment of Active Systemic Lupus Erythematosus (SLE) - A Safety, Tolerability, and Efficacy Study
NCT06514768
/ RecruitingEarly Phase 1IIT
JY231 Injection for the Treatment of B-cell Acute Lymphoblastic Leukemia(B-ALL ) Early Exploratory Clinical Studies on Safety, Tolerability, and Initial Efficacy
100 Clinical Results associated with JY-231
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100 Translational Medicine associated with JY-231
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100 Patents (Medical) associated with JY-231
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100 Deals associated with JY-231
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Systemic Lupus ErythematosusPhase 2
CN
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
09 Oct 2024
Refractory B Acute Lymphoblastic LeukemiaPhase 1
CN
920th Hospital of Joint Logistics Support Force of People's Liberation Army of China
20 Jun 2024
CD19 positive B-Cell LymphomaPhase 1
CN
Guangdong Provincial People's Hospital
18 Aug 2023
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Clinical Result

Indication
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Approval

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Regulation

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