Last update 19 Apr 2025

T-Ama

Overview

Basic Info

Drug Type
Antibody drug conjugate (ADC)
Synonyms
α-amanitin-conjugated trastuzumab
Target
HER2 x RNA polymerase II
Action
antagonists, inhibitors
Mechanism
HER2 antagonists(Receptor protein-tyrosine kinase erbB-2 antagonists), RNA polymerase II inhibitors
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication-
Inactive Indication
HER2-Low Breast Carcinoma
Originator Organization
Indiana UniversityIndiana University
Active Organization-
Inactive Organization
Indiana UniversityIndiana University
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with T-Ama
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100 Translational Medicine associated with T-Ama
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100 Patents (Medical) associated with T-Ama
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1
Literatures (Medical) associated with T-Ama
10 Feb 2021Science translational medicineQ1 · MEDICINE
Targeted immunotherapy for HER2-low breast cancer with 17p loss
Q1 · MEDICINE
100 Deals associated with T-Ama
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HER2-Low Breast CarcinomaPreclinical
United States
Indiana UniversityIndiana University
09 Feb 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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