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Clinical Trials associated with Poliomyelitis (Live) Vaccine Type I Type III (Human Diploid Cell), Oral( Institute of Medical Biology Chinese Academy of Medical Sciences)Trail To Evaluate the Immunity Duration of Different Sequential Immunization Schedules and Effectiveness for Bivalent Oral Poliomyelitis Vaccine Co-administered With IPV Booster Immunization for Poliovirus Vaccine
Trail To Evaluate the Immunity Duration of healthy children who already took part in " The safety and immunogenicity by different sequential schedules of bOPV and bOPV in dragee candy with sIPV, a randomized, double blind, single center and parallel phase Ⅲ clinic trial was performed in Infants of two-month old in Guangxi Province, China" and continue to search for the effects of booster immunization.
Ⅰ型+Ⅲ型口服脊灰减毒活疫苗(液苗/糖丸)(KMB17)与 IPV 序贯接种的抗体免疫持久性及加强免疫效果研究
[Translation] Study on the antibody immunity persistence and booster immunity effect of sequential vaccination with type Ⅰ+type Ⅲ oral attenuated live polio vaccine (liquid vaccine/sugar pill) (KMB17) and IPV
评价Ⅰ型+Ⅲ型口服脊髓灰质炎减毒活疫苗(人二倍体细胞)和Ⅰ型+Ⅲ型脊髓灰质炎减毒活疫苗糖丸(人二倍体细胞)与IPV联合序贯免疫接种的抗体免疫持久性,探索各序贯免疫程序于48月龄时开展加强免疫的合理性。
[Translation] To evaluate the antibody immunity persistence of type 1 + type 3 oral attenuated live polio vaccine (human diploid cells) and type 1 + type 3 polio vaccine sugar pills (human diploid cells) combined with IPV sequential immunization, and to explore the rationality of booster immunization at 48 months of age for each sequential immunization program.
随机、盲法、平行对照试验评价双价脊髓灰质炎减毒活疫苗(人二倍体细胞)与IPV联合序贯免疫临床试验
[Translation] A randomized, blinded, parallel controlled trial to evaluate the sequential immunization of a bivalent attenuated live poliomyelitis vaccine (human diploid cells) combined with IPV
主要目标:比较2剂cIPV/sIPV+1剂tOPV(液体剂型/糖丸)与2剂cIPV/sIPV+1剂bOPV(液体剂型/糖丸)序贯接种后Ⅰ、Ⅱ、Ⅲ型脊髓灰质炎抗体阳转率和抗体水平。 次要目标:(1)比较1剂cIPV/sIPV+2剂tOPV(液体剂型/糖丸)与2剂cIPV/sIPV+1剂bOPV(液体剂型/糖丸)序贯接种后Ⅰ、Ⅱ、Ⅲ型脊髓灰质炎抗体阳转率和抗体水平。(2)评价bOPV(液体剂型/糖丸)疫苗的安全性。
[Translation] Primary objective: To compare the positive conversion rate and antibody levels of polio antibodies of types I, II, and III after sequential vaccination with 2 doses of cIPV/sIPV + 1 dose of tOPV (liquid dosage form/sugar pill) and 2 doses of cIPV/sIPV + 1 dose of bOPV (liquid dosage form/sugar pill). Secondary objectives: (1) To compare the positive conversion rate and antibody levels of polio antibodies of types I, II, and III after sequential vaccination with 1 dose of cIPV/sIPV + 2 doses of tOPV (liquid dosage form/sugar pill) and 2 doses of cIPV/sIPV + 1 dose of bOPV (liquid dosage form/sugar pill). (2) To evaluate the safety of bOPV (liquid dosage form/sugar pill) vaccine.
100 Clinical Results associated with Poliomyelitis (Live) Vaccine Type I Type III (Human Diploid Cell), Oral( Institute of Medical Biology Chinese Academy of Medical Sciences)
100 Translational Medicine associated with Poliomyelitis (Live) Vaccine Type I Type III (Human Diploid Cell), Oral( Institute of Medical Biology Chinese Academy of Medical Sciences)
100 Patents (Medical) associated with Poliomyelitis (Live) Vaccine Type I Type III (Human Diploid Cell), Oral( Institute of Medical Biology Chinese Academy of Medical Sciences)
100 Deals associated with Poliomyelitis (Live) Vaccine Type I Type III (Human Diploid Cell), Oral( Institute of Medical Biology Chinese Academy of Medical Sciences)