Last update 14 Dec 2025

iOlaparib-AP3

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
iOlaparib-AP3
Target
PARP1
Action
degraders
Mechanism
PARP1 degraders(Poly (ADP-Ribose) polymerase 1 degraders)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical Center
Active Organization-
Inactive Organization
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical Center
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC41H42FN7O10
InChIKeyKZECCLCVBAHYOC-UHFFFAOYSA-N
CAS Registry-

Related

100 Clinical Results associated with iOlaparib-AP3
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100 Translational Medicine associated with iOlaparib-AP3
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100 Patents (Medical) associated with iOlaparib-AP3
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100 Deals associated with iOlaparib-AP3
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
United States
The University of Texas Southwestern Medical CenterThe University of Texas Southwestern Medical Center
28 Oct 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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