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Last update 31 Aug 2025
Telmisartan/Amlodipine Besylate/Hydrochlorothiazide
Last update 31 Aug 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms BIBR277TCT, Micatrio, TwoTops Plus + [1] |
Target |
Action antagonists, inhibitors, blockers |
Mechanism AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), VDCCs blockers(Voltage-gated calcium channel blockers) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization- |
Drug Highest PhaseApproved |
First Approval Date Japan (28 Sep 2016), |
Regulation- |
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Structure/Sequence
Molecular FormulaC7H8ClN3O4S2 |
InChIKeyJZUFKLXOESDKRF-UHFFFAOYSA-N |
CAS Registry58-93-5 |
View All Structures (3)
Related
7
Clinical Trials associated with Telmisartan/Amlodipine Besylate/HydrochlorothiazideNCT03021265
The Special Drug Use-results Survey on Long-term Use of Telmisartan 80 mg/Amlodipine 5 mg/Hydrochlorothiazide 12.5 mg Fixed Dose Combination Tablets in Patients With Hypertension
NCT03032315
Clinical Trial to Compare the Pharmacokinetics of TAH Tablet(80/10/12.5mg) in Comparison to the Co-administration of Telmisartan, Amlodipine and Hydrochlorothiazide in Healthy Male Volunteers
NCT02739672
A Randomized, Open-label, Single Dose, Replicate Crossover Clinical Trial to Compare the Pharmacokinetics of TAH Tablet in Comparison to the Co-administration of Telmisartan, Amlodipine and Hydrochlorothiazide in Healthy Male Volunteers
100 Clinical Results associated with Telmisartan/Amlodipine Besylate/Hydrochlorothiazide
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100 Translational Medicine associated with Telmisartan/Amlodipine Besylate/Hydrochlorothiazide
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100 Patents (Medical) associated with Telmisartan/Amlodipine Besylate/Hydrochlorothiazide
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100 Deals associated with Telmisartan/Amlodipine Besylate/Hydrochlorothiazide
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R&D Status
Approved
10 top approved records. to view more data
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| Indication | Country/Location | Organization | Date |
|---|---|---|---|
| Hypertension | Japan | 28 Sep 2016 |
Developing
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Essential Hypertension | Phase 3 | Japan | 01 Nov 2013 |
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Clinical Result
Clinical Result
Indication
Phase
Evaluation
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Phase 1 | - | 36 | HCTZ+Amlodipine+Telmisartan (T80-A5-H12.5) | lefefasjca(qxigyrwnqm) = fdtaxqiqny mkfpdfjqjb (kkqzakspus, 69.3) View more | - | 30 Nov 2016 | |
T80-A5+Amlodipine+Telmisartan (T80-A5) | lefefasjca(qxigyrwnqm) = kpjjjuddut mkfpdfjqjb (kkqzakspus, 70.7) View more | ||||||
Phase 3 | 309 | Placebo+Telmisartan + amlodipine | vilkqpyhqn(aftucpqruk) = jokhwjemne ulwgapianj (vneadjgfzm, 0.5) View more | - | 29 Nov 2016 | ||
Phase 3 | 2,492 | OM/HCTZ | wiohogrfsb(aihtnpagdr) = lqjbjxhbfu xkphhpkzex (bwszhwzewp ) View more | Positive | 01 Jun 2010 |
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