Last update 15 Nov 2025

Ro-60-0759

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
5-HT2C receptor
Action
antagonists
Mechanism
5-HT2C receptor antagonists(Serotonin 2c (5-HT2c) receptor antagonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Anxiety DisordersDepressive DisorderMigraine Disorders+ [1]
Originator Organization
F. Hoffmann-La Roche Ltd.
Active Organization-
Inactive Organization
F. Hoffmann-La Roche Ltd.
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC17H23NO3
InChIKeyXKPFAVXGYLJDLN-KQKSKQCLSA-N
CAS Registry204650-40-8

Related

100 Clinical Results associated with Ro-60-0759
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100 Translational Medicine associated with Ro-60-0759
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100 Patents (Medical) associated with Ro-60-0759
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2
Literatures (Medical) associated with Ro-60-0759
01 Jan 1998HELVETICA CHIMICA ACTA
Syntheses of O‐Methylasparvenone‐Derived Serotonin‐Receptor Antagonists
CHIMIA
Structure-Activity Relationships of Substituted 2,3,4,4a,5,10b-Hexahydro-benz[h]isoquinoline-6(1H)-ones as 5-HT2C Receptor Antagonists
100 Deals associated with Ro-60-0759
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anxiety DisordersPhase 1-
F. Hoffmann-La Roche Ltd.
-
Depressive DisorderPhase 1-
F. Hoffmann-La Roche Ltd.
-
Migraine DisordersPhase 1-
F. Hoffmann-La Roche Ltd.
-
Sleep Wake DisordersPhase 1-
F. Hoffmann-La Roche Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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