Last update 08 May 2025

Anti-EGFRvIII CAR-T-cell therapy (Chembrain LTD/University of Oulu)

Overview

Basic Info

Drug Type
CAR-T
Synonyms-
Target
EGFRvIII
Action
antagonists
Mechanism
EGFRvIII antagonists(Epidermal growth factor receptor variant III antagonists), Immunologic cytotoxicity, T lymphocyte replacements
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Glioblastoma MultiformeMetastatic Malignant Neoplasm to the Leptomeninges
Originator Organization
University of OuluUniversity of Oulu
Active Organization-
Inactive Organization
Chembrain Consults LTDUniversity of OuluUniversity of Oulu
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Anti-EGFRvIII CAR-T-cell therapy (Chembrain LTD/University of Oulu)
NCT05063682
/ Unknown statusPhase 1
A Phase 1 Study to Evaluate EGFRvIII -Targeted Chimeric Antigen Receptor (CAR) T Cells for Adult Patients With Leptomeningeal Glioblastoma
100 Clinical Results associated with Anti-EGFRvIII CAR-T-cell therapy (Chembrain LTD/University of Oulu)
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100 Translational Medicine associated with Anti-EGFRvIII CAR-T-cell therapy (Chembrain LTD/University of Oulu)
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100 Patents (Medical) associated with Anti-EGFRvIII CAR-T-cell therapy (Chembrain LTD/University of Oulu)
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100 Deals associated with Anti-EGFRvIII CAR-T-cell therapy (Chembrain LTD/University of Oulu)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Glioblastoma MultiformePhase 1
Finland
University of OuluUniversity of Oulu
15 May 2020
Glioblastoma MultiformePhase 1
India
University of OuluUniversity of Oulu
15 May 2020
Glioblastoma MultiformePhase 1
Finland
Chembrain Consults LTD
15 May 2020
Glioblastoma MultiformePhase 1
India
Chembrain Consults LTD
15 May 2020
Metastatic Malignant Neoplasm to the LeptomeningesPhase 1
Finland
Chembrain Consults LTD
15 May 2020
Metastatic Malignant Neoplasm to the LeptomeningesPhase 1
Finland
University of OuluUniversity of Oulu
15 May 2020
Metastatic Malignant Neoplasm to the LeptomeningesPhase 1
India
Chembrain Consults LTD
15 May 2020
Metastatic Malignant Neoplasm to the LeptomeningesPhase 1
India
University of OuluUniversity of Oulu
15 May 2020
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Clinical Result

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Approval

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Regulation

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