Last update 25 Apr 2026

APB-A2

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
anti-CD73 human IgG4 antibody (Aprilbio), CD73 checkpoint inhibitor (Aprilbio), APB-A2
Target
CD73
Action
inhibitors
Mechanism
CD73 inhibitors(5-nucleotidase inhibitors)
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease+ [1]
Active Indication
Hepatocellular CarcinomaPancreatic CancerProstatic Cancer+ [1]
Inactive Indication-
Originator Organization
Aprilbio Co. Ltd.Aprilbio Co. Ltd.
Active Organization
Aprilbio Co. Ltd.Aprilbio Co. Ltd.
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Related

100 Clinical Results associated with APB-A2
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100 Translational Medicine associated with APB-A2
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100 Patents (Medical) associated with APB-A2
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100 Deals associated with APB-A2
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatocellular CarcinomaDiscovery
South Korea
Aprilbio Co. Ltd.Aprilbio Co. Ltd.
-
Pancreatic CancerDiscovery
South Korea
Aprilbio Co. Ltd.Aprilbio Co. Ltd.
-
Prostatic CancerDiscovery
South Korea
Aprilbio Co. Ltd.Aprilbio Co. Ltd.
-
Renal Cell CarcinomaDiscovery
South Korea
Aprilbio Co. Ltd.Aprilbio Co. Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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