Last update 21 Nov 2024

Valsartan/Cilnidipine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cilnidipine/valsartan, ATEDIO
+ [1]
Target
AT1R x VDCCs
Mechanism
AT1R antagonists(Angiotensin II Receptor Type 1 antagonists), VDCCs blockers(Voltage-gated calcium channel blockers)
Therapeutic Areas
Cardiovascular Diseases
Active Indication
Hypertension
Inactive Indication-
Originator Organization
EA Pharma Co., Ltd.EA Pharma Co., Ltd.
Active Organization
EA Pharma Co., Ltd.EA Pharma Co., Ltd.
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
JP (24 Mar 2014),
Hypertension
Regulation-
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Structure

Molecular FormulaC24H29N5O3
InChIKeyACWBQPMHZXGDFX-QFIPXVFZSA-N
CAS Registry137862-53-4
View All Structures (2)

Related

7
Clinical Trials associated with Valsartan/Cilnidipine
JPRN-UMIN000019759 / CompletedIIT
Effect of ATEDIO Combination Tab. on hypertension (Retrospective research study) - Hypotensive action (Retrospective research study)
NCT02343250 / CompletedPhase 1
A Randomized, Open-label, Single Dosing, Two-way Crossover Clinical Trial to Compare the Safety/Tolerability and Pharmacokinetics of the Combination of Cilnidipine 10mg and Valsartan 160mg in Comparison to Each Component Coadministered in Healthy Male Volunteers
NCT02145104 / CompletedPhase 3
Comparison of the Efficacy and Safety of Cilnidipine 10mg/Valsartan 160mg Combination Therapy, Cilnidipine 5mg/Valsartan 160mg Combination Therapy and Valsartan 160mg Monotherapy in Hypertensive Patients Inadequately Controlled With Valsartan 160mg Monotherapy: a Multicenter, Randomized, Double Blind Phase III Study
100 Clinical Results associated with Valsartan/Cilnidipine
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100 Translational Medicine associated with Valsartan/Cilnidipine
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100 Patents (Medical) associated with Valsartan/Cilnidipine
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100 Deals associated with Valsartan/Cilnidipine
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External Link

KEGGWikiATCDrug Bank
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C09D
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hypertension
JP
EA Pharma Co., Ltd.EA Pharma Co., Ltd.
24 Mar 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
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Approval

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Regulation

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