Last update 29 Mar 2025

VX-840

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
VX 840, VX840
Target
APOL1
Action
inhibitors
Mechanism
APOL1 inhibitors(Apolipoprotein L1 inhibitors)
Therapeutic Areas
Urogenital Diseases
Active Indication-
Inactive Indication
Apolipoprotein L1-mediated Kidney Disease
Originator Organization
Vertex Pharmaceuticals, Inc.Vertex Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Vertex Pharmaceuticals, Inc.Vertex Pharmaceuticals, Inc.
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with VX-840
NCT05324410
/ CompletedPhase 1
A Phase I, Randomized, Double-blind, Placebo-controlled Study Evaluating the Safety and Pharmacokinetics of Single and Multiple Ascending Doses of VX-840 in Healthy Subjects
100 Clinical Results associated with VX-840
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100 Translational Medicine associated with VX-840
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100 Patents (Medical) associated with VX-840
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100 Deals associated with VX-840
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Apolipoprotein L1-mediated Kidney DiseasePhase 1
United States
Vertex Pharmaceuticals, Inc.Vertex Pharmaceuticals, Inc.
07 Apr 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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