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Last update 09 Aug 2025
TRC-041266
Last update 09 Aug 2025
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms TRC 041266, TRC041266 |
Target |
Action antagonists |
Mechanism AGER antagonists(Advanced glycosylation end product-specific receptor antagonists) |
Therapeutic Areas |
Active Indication- |
Originator Organization |
Active Organization- |
Inactive Organization |
License Organization- |
Drug Highest PhaseDiscontinuedPhase 3 |
First Approval Date- |
Regulation- |
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Related
3
Clinical Trials associated with TRC-041266NCT04507347
Randomized, Double-blind, Placebo-controlled, Parallel-group, Multicentre Study to Evaluate the Efficacy and Safety of TRC041266 Compared to Placebo in Patients With Chronic Stable Heart Failure, an LVEF ≥40%, Moderate to Severe Diastolic Dysfunction and Type 2 Diabetes Mellitus
CTRI/2020/04/024708
An Open Label, Randomized, Multiple-dose, Crossover Study to Compare the OralPharmacokinetics and Safety of TRC041266 Powder with TRC4186 Tablet in HealthyHuman Subjects.
CTRI/2018/08/015226
An Open Label, Randomized, Crossover Study to Compare the Pharmacokinetics of TRC041266 Powder with TRC4186 Tablet under Fasting Condition and to Evaluate the Effect of Food on the Pharmacokinetics of TRC041266 Powder in Healthy Human Subjects
100 Clinical Results associated with TRC-041266
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100 Translational Medicine associated with TRC-041266
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100 Patents (Medical) associated with TRC-041266
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100 Deals associated with TRC-041266
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Chronic heart failure | Phase 3 | - | 01 Jun 2021 | |
| Diabetes Mellitus, Type 2 | Phase 3 | - | 01 Jun 2021 | |
| Heart failure with normal ejection fraction | Phase 3 | - | 01 Jun 2021 |
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