Pemirolast Potassium

The safety of food of animal origin is closely related to feed quality. Feed pollution by brominated flame retardants (BFRs) leads to the exposure of animals and consumers of food of animal origin to these substances. The study aimed to assess the concentration of ten PBDE (BDE-28, 47, 49, 99, 100, 138, 153, 154, 183, and 209) congeners and eight nBFRs (TBX, PBT, HBB, PBEB, EH-TBB, BTBPE, BEH-TBPH, and DBDPE) in 59 feed and feed materials from six different feed categories (277/2012/EU). The quantification of analytes was based on isotopic dilution and gas chromatography-high-resolution mass spectrometry (GC-HRMS). All 59 feed samples were contaminated with at least one of the analytes. PBDEs and nBFRs were found in 78% and 91% of the samples, respectively. BFR content ranged from 0.18 to 5.87 μg kg^-1 in feed with a 12% moisture content, and the most contaminated category was vegetable oils, followed by fishmeal, feeds for fish, animal fats, and compound feeds for pigs. The least contaminated samples turned out to be compound feeds for chickens. This study confirms the general trend of decreasing PBDE concentrations in fishmeal. In the investigated samples, BDE-47 and BDE-209 contributed the most to the ∑PBDE content. DBDPE, HBB, and PBT contributed the most to the investigated ∑nBFRs. The widespread occurrence of nBFRs in feed seems disturbing because these compounds have replaced PBDEs. Their concentrations in the feed may most likely exceed those of PBDEs in the coming years.