Last update 08 May 2025

PT-65

Overview

Basic Info

Drug Type
Proteolysis-targeting chimeras (PROTAC)
Synonyms
Target
GSK-3
Action
inhibitors
Mechanism
GSK-3 inhibitors(Glycogen synthase kinase-3 inhibitors)
Therapeutic Areas
Nervous System Diseases
Active Indication
Alzheimer Disease
Inactive Indication-
Originator Organization
China Pharmaceutical UniversityChina Pharmaceutical University
Active Organization
China Pharmaceutical UniversityChina Pharmaceutical University
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC51H63N13O12S
InChIKeyQJSFLEBIQZMJQF-UHFFFAOYSA-N
CAS Registry2721998-87-2

Related

100 Clinical Results associated with PT-65
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100 Translational Medicine associated with PT-65
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100 Patents (Medical) associated with PT-65
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1
Literatures (Medical) associated with PT-65
01 Dec 2021European Journal of Medicinal ChemistryQ1 · MEDICINE
Discovery of PT-65 as a highly potent and selective Proteolysis-targeting chimera degrader of GSK3 for treating Alzheimer's disease
Q1 · MEDICINE
100 Deals associated with PT-65
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePreclinical
China
China Pharmaceutical UniversityChina Pharmaceutical University
01 Dec 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Clinical Trial

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Approval

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Regulation

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