[Translation] A single-center, randomized, double-blind, placebo-controlled Phase I clinical study to evaluate the safety, tolerability and pharmacokinetic characteristics of single and multiple ascending doses of ACT500 (formerly known as NM6606) in healthy Chinese adult subjects
1.评估ACT500在健康成年受试者中单次和多次口服给药的安全性和耐受性;
2.评估ACT500及其代谢物在健康成年受试者中单次和多次口服给药的药代动力学(PK)特征;
3.探索ACT500在健康成年受试者中单次和多次口服给药的代谢产物和生物标志物。
[Translation] 1. Evaluate the safety and tolerability of ACT500 after single and multiple oral administration in healthy adult subjects;
2. Evaluate the pharmacokinetic (PK) characteristics of ACT500 and its metabolites after single and multiple oral administration in healthy adult subjects;
3. Explore the metabolites and biomarkers of ACT500 after single and multiple oral administration in healthy adult subjects.