Last update 28 May 2025

Travoprost/Verosudil

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
AR-12286/travoprost, Travoprost/AR-12286, Verosudil/travoprost
+ [1]
Target
PTGFR x ROCK
Action
agonists, inhibitors
Mechanism
PTGFR agonists(Prostanoid FP receptor agonists), ROCK inhibitors(Rho-associated kinases inhibitors)
Therapeutic Areas
Eye Diseases
Active Indication-
Inactive Indication
Glaucoma, Open-Angle
Originator Organization
Aerie Pharmaceuticals, Inc.Aerie Pharmaceuticals, Inc.
Active Organization-
Inactive Organization
Aerie Pharmaceuticals, Inc.Aerie Pharmaceuticals, Inc.
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC26H35F3O6
InChIKeyMKPLKVHSHYCHOC-AHTXBMBWSA-N
CAS Registry157283-68-6
View All Structures (2)

Related

2
Clinical Trials associated with Travoprost/Verosudil
NCT01789736
/ CompletedPhase 2
A Study Assessing the Safety and Ocular Hypotensive Efficacy of PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components
NCT01474135
/ CompletedPhase 2
A Double-masked, Randomized, Controlled Study Assessing the Safety and Ocular Hypotensive Efficacy of Two AR 12286/Travoprost Fixed-dose Combination Products Compared to Travatan® Z in Patients With Elevated Intraocular Pressure
100 Clinical Results associated with Travoprost/Verosudil
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100 Translational Medicine associated with Travoprost/Verosudil
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100 Patents (Medical) associated with Travoprost/Verosudil
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100 Deals associated with Travoprost/Verosudil
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Glaucoma, Open-AnglePhase 2
United States
Aerie Pharmaceuticals, Inc.Aerie Pharmaceuticals, Inc.
01 Dec 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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