Last update 30 Aug 2025

xl-400

Overview

Basic Info

Drug Type
Fusion protein, Enzyme
Synonyms
PASylated recombinant uricase(Horizon), HZN-007, XL-400
Target
Uric acid
Action
modulators
Mechanism
Uric acid modulators(Uric acid modulators)
Therapeutic Areas
Immune System DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication-
Inactive Indication
Gout
Originator Organization
XL-protein GmbHXL-protein GmbH
Active Organization-
Inactive Organization
Horizon Therapeutics Ltd. (Ireland)XL-protein GmbHXL-protein GmbH
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with xl-400
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100 Translational Medicine associated with xl-400
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100 Patents (Medical) associated with xl-400
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100 Deals associated with xl-400
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
GoutPreclinical
Ireland
Horizon Therapeutics Ltd. (Ireland)
23 Aug 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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