Last update 08 May 2025

xl-400

Overview

Basic Info

Drug Type
Fusion protein, Enzyme
Synonyms
PASylated recombinant uricase(Horizon)
Target
Uric acid
Action
modulators
Mechanism
Uric acid modulators(Uric acid modulators)
Therapeutic Areas
Immune System DiseasesCongenital DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication-
Inactive Indication
Gout
Originator Organization
XL-protein GmbHXL-protein GmbH
Active Organization-
Inactive Organization
Horizon Therapeutics Ltd. (Ireland)XL-protein GmbHXL-protein GmbH
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with xl-400
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100 Translational Medicine associated with xl-400
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100 Patents (Medical) associated with xl-400
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100 Deals associated with xl-400
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
GoutPreclinical
Ireland
Horizon Therapeutics Ltd. (Ireland)
23 Aug 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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