Last update 29 Mar 2025

KOS-2187

Overview

Basic Info

Drug Type
Synthetic peptide
Synonyms
KOS 2187, PF-04548043, PF-4548043
Target
GPR38
Action
agonists
Mechanism
GPR38 agonists(Motilin receptor agonists)
Therapeutic Areas
Nervous System DiseasesDigestive System DisordersEndocrinology and Metabolic Disease+ [2]
Active Indication-
Inactive Indication
Diabetic GastroparesisGastroesophageal Reflux
Originator Organization
Kosan Biosciences, Inc.Kosan Biosciences, Inc.
Active Organization-
Inactive Organization
Pfizer Inc.Pfizer Inc.Kosan Biosciences, Inc.Kosan Biosciences, Inc.
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with KOS-2187
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100 Translational Medicine associated with KOS-2187
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100 Patents (Medical) associated with KOS-2187
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100 Deals associated with KOS-2187
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Diabetic GastroparesisPhase 1
United States
Pfizer Inc.Pfizer Inc.
-
Gastroesophageal RefluxPhase 1
United States
Pfizer Inc.Pfizer Inc.
-
Gastroesophageal RefluxPhase 1-
Kosan Biosciences, Inc.Kosan Biosciences, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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