Last update 08 May 2025

Bendroflumethiazide/Nadolol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nadolol/Bendroflumethiazide, Corzide
Target
NCC x β1-adrenergic receptor x β2-adrenergic receptor
Action
inhibitors, antagonists
Mechanism
NCC inhibitors(Thiazide-sensitive sodium-chloride cotransporter inhibitors), β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists), β2-adrenergic receptor antagonists(Beta-2 adrenergic receptor antagonists)
Therapeutic Areas
Cardiovascular Diseases
Active Indication-
Inactive Indication
Hypertension
Originator Organization
Pfizer Inc.Pfizer Inc.
Active Organization-
Inactive Organization
King Pharmaceuticals LLCKing Pharmaceuticals LLC
License Organization-
Drug Highest PhaseWithdrawn
First Approval Date
United States (25 May 1983),
Hypertension
Regulation-
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Structure/Sequence

Molecular FormulaC15H14F3N3O4S2
InChIKeyHDWIHXWEUNVBIY-UHFFFAOYSA-N
CAS Registry73-48-3
View All Structures (2)

Related

2
Clinical Trials associated with Bendroflumethiazide/Nadolol
NCT00648297
/ CompletedPhase 1
Single-Dose Fed Bioequivalence Study of Nadolol/Bendroflumethiazide Tablets (80 mg/5 mg; Mylan) and Corzide® Tablets (80 mg/5 mg; King) in Healthy Volunteers
NCT00647660
/ CompletedPhase 1
Single-Dose Fasting Bioequivalence Study of Nadolol/Bendroflumethiazide Tablets (80 mg/5 mg; Mylan) to Corzide® Tablets (80 mg/5 mg; King) in Healthy Volunteers
100 Clinical Results associated with Bendroflumethiazide/Nadolol
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100 Translational Medicine associated with Bendroflumethiazide/Nadolol
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100 Patents (Medical) associated with Bendroflumethiazide/Nadolol
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100 Deals associated with Bendroflumethiazide/Nadolol
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External Link

KEGGWikiATCDrug Bank
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C07BA12
-

R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Approval

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Regulation

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