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Last update 08 Nov 2025
HY-004 (Juventas)
Last update 08 Nov 2025
Overview
Basic Info
Drug Type Autologous CAR-T |
Synonyms Anti-CD19/CD20 CAR-T cell therapy (Juventas Cell Therapy), CD19/CD20 CART cell therapy (Juventas Cell Therapy), CD19/CD20 chimeric antigen receptor Tcell therapy (Juventas Cell Therapy) + [2] |
Target |
Action inhibitors |
Mechanism CD19 inhibitors(B-lymphocyte antigen CD19 inhibitors), CD20 inhibitors(B-lymphocyte antigen CD20 inhibitors), Gene transference(Gene transference) |
Therapeutic Areas |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
4
Clinical Trials associated with HY-004 (Juventas)NCT06005649
A Multi-center, Open Label, Single-arm, Phase I/II Clinical Trial of HY004 Cell Injection in the Treatment of Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma
NCT06009107
A Phase I/II, Single Arm, Multi-center Study Evaluating the Safety and Efficacy of HY004 in Adult Patients With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r B-ALL)
CTR20232686
HY004细胞注射液治疗成人CD19和/或CD22阳性的复发或难治性B细胞非霍奇金淋巴瘤的多中心、开放、单臂、Ⅰ/Ⅱ期临床试验
[Translation] A multicenter, open, single-arm, phase I/II clinical trial of HY004 cell injection for the treatment of adult patients with CD19 and/or CD22-positive relapsed or refractory B-cell non-Hodgkin's lymphoma
100 Clinical Results associated with HY-004 (Juventas)
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100 Translational Medicine associated with HY-004 (Juventas)
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100 Patents (Medical) associated with HY-004 (Juventas)
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100 Deals associated with HY-004 (Juventas)
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| B-cell lymphoma refractory | Phase 2 | - | 01 Sep 2025 | |
| High grade B-cell lymphoma | Phase 2 | - | 01 Sep 2025 | |
| Mediastinal large B-cell lymphoma | Phase 2 | - | 01 Sep 2025 | |
| Pre B-cell acute lymphoblastic leukemia | Phase 2 | - | 30 Jun 2025 | |
| CD19-positive B-cell acute lymphoblastic leukemia | Phase 1 | China | 26 Sep 2023 | |
| CD22 Positive B-cell Acute Lymphoblastic Leukemia | Phase 1 | China | 26 Sep 2023 | |
| Diffuse Large B-Cell Lymphoma | Phase 1 | China | 30 Aug 2023 |
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