Last update 11 Oct 2025

KT127

Overview

Basic Info

Drug Type
Autologous CAR-T
Synonyms-
Target
MSLN
Action
inhibitors
Mechanism
MSLN inhibitors(Mesothelin inhibitors)
Therapeutic Areas
NeoplasmsEndocrinology and Metabolic DiseaseUrogenital Diseases
Active Indication
Platinum-Resistant Ovarian Carcinoma
Inactive Indication-
Originator Organization
Nanjing Kati Medical Technology Co., Ltd.Nanjing Kati Medical Technology Co., Ltd.
Active Organization
Southeast University Affiliated Zhonda HospitalSoutheast University Affiliated Zhonda Hospital
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1/2
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with KT127
NCT05963100
/ Active, not recruitingPhase 1/2IIT
Clinical Study of TCR-like CAR-T Cell Targeted MSLN in the Treatment of Ovarian Cancer
100 Clinical Results associated with KT127
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100 Translational Medicine associated with KT127
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100 Patents (Medical) associated with KT127
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100 Deals associated with KT127
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Platinum-Resistant Ovarian CarcinomaPhase 2
China
Southeast University Affiliated Zhonda HospitalSoutheast University Affiliated Zhonda Hospital
07 Aug 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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