Last update 21 Oct 2026

Padoprazan

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DW-4421, ID-120040002, ID120040002
Target
H+/K+ ATPase
Action-
Mechanism
P-CAB(Potassium-competitive acid blockers)
Therapeutic Areas
Digestive System DisordersMouth and Tooth DiseasesOtorhinolaryngologic Diseases+ [1]
Active Indication
Non-erosive gastro-esophageal reflux diseaseErosive gastro-esophageal reflux diseaseGastroesophageal Reflux
Inactive Indication-
Originator Organization
Ildong Pharmaceutical Co., Ltd.Ildong Pharmaceutical Co., Ltd.
Active Organization
Daewon Pharmaceutical Co., Ltd.Daewon Pharmaceutical Co., Ltd.Ildong Pharmaceutical Co., Ltd.Ildong Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization
Yunovia Co. Ltd.Daewon Pharmaceutical Co., Ltd.Daewon Pharmaceutical Co., Ltd.
Drug Highest PhasePhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC19H20FN3O4S
InChIKeyUDMABANYJMEZDH-UHFFFAOYSA-N
CAS Registry2756367-23-2

Related

7
Clinical Trials associated with Padoprazan
NCT07691242
/ Not yet recruitingPhase 1
A Phase 1 Clinical Trial to Evaluate the Safety, the Pharmacokinetics and Pharmacodynamics After Multiple Administration of DW4421 in Healthy Adult Volunteers
NCT07364851
/ Not yet recruitingPhase 1
A Randomized, Open-label, Single-dose, 2-sequence, Two-period, Crossover Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics After Administration of DW4421-T1 and DW4421S-T1 in Healthy Adult Volunteers
NCT07382661
/ Not yet recruitingPhase 1
A Phase 1 Clinical Trial to Evaluate the Safety and the Pharmacokinetics Drug-drug Interaction of DW4421 and Amoxicillin/Clarithromycin in Healthy Adult Volunteers
100 Clinical Results associated with Padoprazan
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100 Translational Medicine associated with Padoprazan
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100 Patents (Medical) associated with Padoprazan
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100 Deals associated with Padoprazan
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-erosive gastro-esophageal reflux diseasePhase 3
South Korea
Daewon Pharmaceutical Co., Ltd.Daewon Pharmaceutical Co., Ltd.
27 Oct 2025
Erosive gastro-esophageal reflux diseasePhase 3
South Korea
Daewon Pharmaceutical Co., Ltd.Daewon Pharmaceutical Co., Ltd.
15 Oct 2025
Gastroesophageal RefluxPhase 2
South Korea
Ildong Pharmaceutical Co., Ltd.Ildong Pharmaceutical Co., Ltd.
01 Nov 2022
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Clinical Result

Indication
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Evaluation
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Approval

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Regulation

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