Last update 20 Mar 2025

Neoepitope-based immunotherapies(Advaxis, Inc.)

Overview

Basic Info

Drug Type
Recombinant vector vaccine, Prophylactic vaccine
Synonyms
ADXS NEO, ADXS-NEO, Neoepitope-based immunotherapies
Target-
Action
stimulants
Mechanism
Gene transference, Immunostimulants
Therapeutic Areas
NeoplasmsDigestive System DisordersUrogenital Diseases
Active Indication
Bladder CancerColorectal Cancer
Inactive Indication
Head and neck cancer metastaticMetastatic colon cancerMetastatic melanoma+ [3]
Originator Organization
Advaxis, Inc.Advaxis, Inc.
Active Organization
Amgen, Inc.Amgen, Inc.
Inactive Organization
Advaxis, Inc.Advaxis, Inc.
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with Neoepitope-based immunotherapies(Advaxis, Inc.)
NCT03265080
/ TerminatedPhase 1
A Phase 1 Dose-Escalation Study of ADXS-NEO Expressing Personalized Tumor Antigens, Alone and in Combination With Pembrolizumab in Subjects With Advanced or Metastatic Solid Tumors
100 Clinical Results associated with Neoepitope-based immunotherapies(Advaxis, Inc.)
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100 Translational Medicine associated with Neoepitope-based immunotherapies(Advaxis, Inc.)
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100 Patents (Medical) associated with Neoepitope-based immunotherapies(Advaxis, Inc.)
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100 Deals associated with Neoepitope-based immunotherapies(Advaxis, Inc.)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Bladder CancerPhase 1-
Amgen, Inc.Amgen, Inc.
-
Colorectal CancerPhase 1-
Amgen, Inc.Amgen, Inc.
-
Head and neck cancer metastaticPreclinical
United States
Advaxis, Inc.Advaxis, Inc.
28 Mar 2018
Metastatic colon cancerPreclinical
United States
Advaxis, Inc.Advaxis, Inc.
28 Mar 2018
Metastatic melanomaPreclinical
United States
Advaxis, Inc.Advaxis, Inc.
28 Mar 2018
metastatic non-small cell lung cancerPreclinical
United States
Advaxis, Inc.Advaxis, Inc.
28 Mar 2018
Metastatic Solid TumorPreclinical
United States
Advaxis, Inc.Advaxis, Inc.
28 Mar 2018
Transitional Cell CarcinomaPreclinical
United States
Advaxis, Inc.Advaxis, Inc.
28 Mar 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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