Last update 08 May 2025

NBI-27155

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
CRHR1
Action
antagonists
Mechanism
CRHR1 antagonists(Corticotropin-releasing factor receptor 1 antagonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Anxiety DisordersDepressive Disorder, Major
Originator Organization
Neurocrine Biosciences, Inc.Neurocrine Biosciences, Inc.
Active Organization-
Inactive Organization
Neurocrine Biosciences, Inc.Neurocrine Biosciences, Inc.
License Organization-
Drug Highest PhaseDiscontinuedPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC23H31N3O3
InChIKeyVVOKUTLMKHSKLC-UHFFFAOYSA-N
CAS Registry186342-55-2

Related

100 Clinical Results associated with NBI-27155
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100 Translational Medicine associated with NBI-27155
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100 Patents (Medical) associated with NBI-27155
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1
Literatures (Medical) associated with NBI-27155
01 May 2004Bioorganic & Medicinal Chemistry LettersQ4 · MEDICINE
Design, synthesis, and SAR of 2-dialkylamino-4-arylpyrimidines as potent and selective corticotropin-releasing factor 1 (CRF 1 ) receptor antagonists
Q4 · MEDICINE
100 Deals associated with NBI-27155
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anxiety DisordersPhase 1-
Neurocrine Biosciences, Inc.Neurocrine Biosciences, Inc.
-
Anxiety DisordersPhase 1
United States
Neurocrine Biosciences, Inc.Neurocrine Biosciences, Inc.
-
Depressive Disorder, MajorPhase 1
United States
Neurocrine Biosciences, Inc.Neurocrine Biosciences, Inc.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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