Brain tumours are responsible for more deaths in children and adults under the age of 40 than any other cancer. The TriNetra-Glio blood test works to isolate tumour cells that have broken free from the circulating tumour in the blood. The isolated cells are then stained and identified under a microscope. Responsible for more than 300,000 new cases worldwide every year, GBM is a form of cancer that starts as a growth of cells in the brain or spinal cord and quickly grows, invading and destroying healthy tissues. Furthermore, it could replace the need for surgical biopsies, which carry significant risks, particularly for those with underlying health issues.
Dr Nelofer Syed, department of brain sciences, ICL and leader of the Brain Tumour Research Centre, commented: “Through this technology, a diagnosis of inaccessible tumours can become possible through a risk-free and patient-friendly blood test.” "This could help speed up diagnosis, enabling surgeons to apply tailored treatments based on that biopsy to increase patients’ chances of survival,” said Kevin O’Neill, consultant neurosurgeon, Imperial College NHS Healthcare Trust and honorary clinical senior lecturer, department of brain sciences, ICL.
Syed added: “We believe this would be a world-first as there are currently no non-invasive or non-radiological tests for these types of tumours.”
Researchers now hope to conduct a larger study in the UK. If successful, patients living with suspected high-grade tumours could benefit from this work within two years.