Johnson & Johnson’s oral antiviral has shown hints of activity in a Phase IIa human challenge trial for the prevention of mosquito-borne diseasedengue fever, a category historically riddled with challenges.
The trial is studying three dosing regimens of JNJ-1802 versus placebo in 54 healthy adults at sites in more than 10 countries. The subjects received treatment or placebo daily and were exposed to attenuated dengue 3 serotype (DENV-3) five days in. They continued to get daily treatment or placebo for 26 days.
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Source: EndPoints
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