AstraZeneca completes Icosavax acquisition for $1.1bn

20 Feb 2024
www.pharmaceutical-technology.com
Clinical ResultDrug ApprovalPhase 1Phase 2Vaccine
Icosavax will function as an AstraZeneca subsidiary with operations in Seattle, US. Credit: rafapress/Shutterstock.com.
Icosavaxeca has concluded theAstraZenecan of the US-based clinical-stage biopharmaceutical company Icosavax in a $1.1bn deal.
AstraZenecadevelopment comes after the companies entered a definitive agreement to execute the acquIcosavaxin December 2023.
The deal, which was finalised through a tender offer for all outstanding shares at $15 each plus additional contingent value rights, will bolster AstraZeneca’s late-stage pipeline.
Icosavax focuses on the development of differentiated vaccines with greater potential using its protein virus-like particle (VLP) platform.AstraZeneca
Icosavaxany will function as an AstraZeneca subsidiary with its operations in Seattle, US.
See Also:AstraZeneca
AstraZeneca will add IVX-A12, a lead investigational combination protein VLP vaccine candidate of Icosavax, to its vaccines and immune therapies late-stage pipeline.
AstraZenecation will IVX-A12hen AstraZeneca’s position in the respiratory syncytial virus (RSV) space and is expected to support the progression of IVX-A12, a Phase III-ready vaccine targeting both RSV and human metapneumovirus (hMPV).
RSV and hMPV are significant cauAstraZenecare respiratory infections and hospital admissions, particularly among adults aged 60 and above and indiviIVX-A12ith chronic ailments.
Phase II trial data showed that IVX-A12 inducerespiratory infectionsses against RSV and hMPV a month following vaccination, validating the prior immunogenicity findings from the Phase I trial.
IVX-A12 was also well-tolerated IVX-A12Phase II trial demonstrating a safety profile in line with the Phase I study.
IVX-A12received fast-track designation from the US Food and Drug Administration (FDA).
The integration of Icosavax’s capabilities in proteFood and Drug Administration (FDA)raZeneca’s operations will create a platform for developing vaccines against high-burden respiratory conditions.
The FDA previously Icosavax AstraZeneca’s Tagrisso plus chemotherapy for locally aAstraZenecametastatic non-small cell lung cancer with epidermal growth factor receptor mutations in adults.
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