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MechanismFGFR4 antagonists |
Active Org.- |
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Active Indication- |
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Drug Highest PhasePending |
First Approval Ctry. / Loc.- |
First Approval Date- |
一项评价ICP-105在实体瘤受试者中的安全性、耐受性、药代动力学的单中心、非随机、开放性I期临床试验
[Translation] A single-center, non-randomized, open-label Phase I clinical trial to evaluate the safety, tolerability, and pharmacokinetics of ICP-105 in subjects with solid tumors
主要目的:评估ICP-105胶囊在实体瘤受试者中的安全性和耐受性、通过剂量递增试验确定推荐后续研究用药剂量 次要目的: 1.评价口服ICP-105胶囊在实体瘤受试者中单次给药和连续给药的药代动力学特征 2.评价食物对口服ICP-105胶囊的药代动力学的影响
[Translation] Primary objectives: To evaluate the safety and tolerability of ICP-105 capsules in subjects with solid tumors and determine the recommended subsequent study dose through a dose escalation study Secondary objectives: 1. To evaluate the pharmacokinetic characteristics of single and continuous administration of oral ICP-105 capsules in subjects with solid tumors 2. To evaluate the effect of food on the pharmacokinetics of oral ICP-105 capsules
100 Clinical Results associated with Nanjing Tianyin Jianhua Pharmaceutical Technology Co., Ltd.
0 Patents (Medical) associated with Nanjing Tianyin Jianhua Pharmaceutical Technology Co., Ltd.
100 Deals associated with Nanjing Tianyin Jianhua Pharmaceutical Technology Co., Ltd.
100 Translational Medicine associated with Nanjing Tianyin Jianhua Pharmaceutical Technology Co., Ltd.