Objective To explore the application of fetal growth parameters measured by ultrasound in fetal weight prediction.Methods A total of 500 healthy pregnant women whose fetal weight was estimated by ultrasonic measurement system within 72 h of full-term delivery from Jan. 2017 to Dec. 2019 in Dongguan Guangji Hospital and Dongguan Jinmeiji Women′s and Children′s Hospital were retrospectively selected as research objects.The biparietal diameter(BPD), head circumference(HC), abdominal circumference(AC) and femur length(FL) of the fetus were measured by ultrasound from 36 wk to 41 wk of pregnancy, and compared with the actual weight of the baby within 72 h of birth.The equation for predicting fetal weight was obtained by unit and multiple linear regression anal.Results Combining the indexes of BPD, HC, AC and FL, the correlation between the predicted fetal weight and the actual birth weight was the highest(r=0.933).The coincidence rate between the predicted fetal weight and the actual birth weight was 83.2%.Conclusion The application of ultrasonic measurement system to predict fetal weight is simple and accurate, which can improve the one-sidedness of other methods in fetal measurement, the objectivity and accuracy of the overall measurement index and better serve the clinic.

Xiandai Zhenduan Yu Zhiliao

Efficacy and safety of montelukast sodium combined with aminophylline in treatment of bronchial asthma and impact on pulmonary function

Author: Li, Ping-sheng ; Zhang, Zhi ; Xu, Guo-qiu

Objective: To investigate the efficacy and safety of montelukast sodium combined with aminophylline in treatment of bronchial asthma and impact on pulmonary function.Methods: 100 cases of patients with bronchial asthma were divided into a control group and an observation group.The control group received conventional therapy + aminophylline i.v. drip, while the observation group received oral montelukast sodium addnl.Results: After treatment, the FVC, FEV1, and FEV1/FVC in the observation group were significantly higher than those in the control group.There was no significant difference in the incidence of adverse reactions between the groups.Conclusion: For the patients with bronchial asthma, montelukast sodium combined with aminophylline can effective improve pulmonary function, and shows high safety.

Shengzhi Yixue Zazhi

Comparison of therapeutic effect of two intrauterine perfusion treatments on patients with thin endometrium

Author: Long Hui-dong ; Huang Yu-qun ; Deng Wei-fen ; Wu Di ; Wang Feng ; Li Yu-bin

Objective:To compare the therapeutic effects of intrauterine perfusion treatments with platelet rich plasma(PRP) or granulocyte colony stimulating factor(G-CSF) on thin endometrium patients undergoing IVF-ET.Methods:The thin endometrium patients undergoing frozen embryo transfer in our reproductive center from July 2018 to March 2020 were randomly divided into three groups:PRP intrauterine perfusion(PRP group,n=80),G-CSF intrauterine perfusion(G-CSF group,n=81) and normal saline intrauterine perfusion(control group,n=68).The platelet concentration in whole blood of PRP group was measured to test the effectiveness of PRP preparationThe general condition,endometrium thickness and blood flow classification,embryo implantation rate,clin. pregnancy rate and early miscarriage rate were compared among the three groups.Results:There was no significant difference in basic general conditions among the three groups(P>0.05).The platelet concentration in PRP was significantly higher than that in whole blood in PRP group [(433.83±36.76)x10∼9/L vs.(137.17±24.94)x10∼9/L](P<0.001).There was no significant difference in endometrial thickness in the previous cycle among the three groups(P>0.05).The thickness of endometrium on embryo transfer day after intrauterine perfusion in PRP group and G-CSF group was(7.84±0.88) mm and(7.60±0.86) mm,resp.,which were significantly higher than that before treatment(P<0.001).There was no significant difference between the two groups(P>0.05),but those were all significantly higher than the control group(6.98±0.65)(P<0.001).The proportion of patients with grade B and C blood flow after therapy in PRP group and G-CSF group was significantly higher than that in the control group(P<0.05).There was no significant difference in the number of embryo transferred,embryo implantation rate,clin. pregnancy rate and early miscarriage rate among the three groups(P>0.05).Conclusions:PRP and G-CSF intrauterine perfusion can significantly promote the growth of thin endometrium and improve endometrium blood flow,and the effect of the two methods is similar,but the clin. pregnancy rate is not significantly improved.

100 Deals associated with Dongguan Guangji Hospital Co. Ltd.

100 Translational Medicine associated with Dongguan Guangji Hospital Co. Ltd.

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