Crompton Manufacturing Co., Inc.

Seven N-aryl-5,6-dihydro-3-methyl-1,4-dioxin-2-carboxamides were prepared as potential fungicides.The fungicidal activity of the dioxincarboxamides was evaluated against bean rust, a major disease of cereal crops.Structure-activity relationships for the screened compounds are discussed.The fungicidal activity of the dioxincarboxamides is correlated with that of the structurally similar com. fungicide, carboxin.

Using a laboratory technique previously developed to evaluate the performance of chem. foaming agents (CFAs) in crosslinked polyethylene (XLPE) foam, metallocene polyolefins were evaluated at various addition levels to branched LDPE to determine their effect on general foam quality (cell size, d., appearance etc.).The laboratory method is discussed, and conclusions on acceptable levels of the metallocene resins are offered.

The aerobic soil metabolism of [¹⁴C]flupropacil was determined in microbially active, sieved (2-mm) sandy loam soil with a soil moisture content of 75% at 1/3 bar.The soil was treated with [¹⁴C]flupropacil at 0.5 mg kg^-1 (twice the field use rate) and placed in incubation flasks connected to a series of traps (50 g L^-1 NaOH, 0.5 M H₂SO₄, ethylene glycol) and incubated at 25(±1)°C.Soil was sampled at 0, 3, 9, 20, 30, 48, 76, 120, 181 and 238 days of aerobic incubation.Volatiles were collected once every two weeks and on the day of soil sampling.Flupropacil metabolized with a half-life of 79 days under aerobic conditions.The major metabolite was flupropacil acid which accounted for up to 69.1% of the initially applied radioactivity at day 238.Each of the two minor metabolites detected at the end of the study accounted for less than 0.5%.One of the minor metabolites was identified as C4242 acid (2-chloro-5-(1,2,3,6-tetrahydro-2,6-dioxo-4-trifluoromethylpyrimidin-1-yl)benzoic acid).Only a negligible portion (< 0.3%) and of the applied flupropacil was mineralized to [¹⁴C]carbon dioxide.Extractable radioactivity ranged from 78.9% to 95.5%, with bound residues accounting for 3.2%-23.4%.The material balance ranged from 91.6% to 104.4%.