[Translation] An interventional, randomized, open-label, parallel-group, single-dose trial to investigate the safety, immunogenicity, tolerability, and pharmacokinetic characteristics of Lu AF82422 in healthy Chinese and healthy Caucasian participants
本试验的主要目标是了解以下几个方面:a) Lu AF82422的安全性和耐受性(参与者在治疗过程中是否出现任何新的或加重的医疗问题),b) Lu AF82422的免疫原性(药物引发不良免疫反应的可能性),c) Lu AF82422的药代动力学参数(药物在体内的吸收、分布和代谢过程)。在试验期间,健康的成年参与者(中国和高加索人)将接受一次Lu AF82422的静脉输注。
[Translation] The main objectives of this trial are to understand the following aspects: a) the safety and tolerability of Lu AF82422 (whether participants develop any new or worsening medical problems during treatment), b) the immunogenicity of Lu AF82422 (the possibility of the drug triggering an adverse immune response), and c) the pharmacokinetic parameters of Lu AF82422 (the absorption, distribution, and metabolism of the drug in the body). During the trial, healthy adult participants (Chinese and Caucasian) will receive a single intravenous infusion of Lu AF82422.