Stem cell culture is based on empirical visual cell management, and it has been common sense for many years to perform operations such as manual medium replacement.In addition, even nowadays when regenerative medicine is actively carried out, most of the cell culture processing for manual treatment is performed.However, in the large-scale production and manufacturing of cell processed products and regenerative medicine products after the safety and efficacy have been confirmed, it is necessary to manufacture cell placements that cannot be performed manually, so that it is not the transformation of the industry has become a major issue in future industrialization.First, in order to achieve quality stabilization, a robot-controlled incubator was developed, but since the main focus is on the stable imitation of human work, it is still far from overcoming problems in processing and cosmetics.Our company can automatically culture more than 100 million (10 '8) stem cells required for treatment, the culture state can be grasped by monitoring, and it can be operated with low cost and low power consumption.We will report on the development of a next-generation culture device.