Scil Proteins GmbH

Halle (Saale), Germany – 3rd Feb 2017 – Scil Proteins GmbH, the expert protein engineering company for affinity ligands and targeted carriers, today announced that UV-Cap GmbH & Co KG, Ravensburg, has acquired 100% of the shares of Scil Proteins from Bionet Ventures GmbH, Munich. The Company will be renamed to Navigo Proteins GmbH. All staff and management will be retained.The new Navigo Proteins will operate through two separate business units; Navigo Precision Targeting and Navigo Precision Capturing®. Navigo Precision Targeting will focus on diagnostics, imaging and therapeutics, whilst Navigo Precision Capturing® will produce affinity products for biopharmaceutical manufacturing. This structure will support continued growth and accelerate Navigo Proteins’ commercialisation strategy. Henning Afflerbach, CEO of Navigo Proteins stated: “This is a natural next growth step in the evolution and value creation strategy for our business. UV-Cap’s global industry network and in-depth knowledge of the biopharmaceutical sector will further support our mission to provide novel targeted molecules for use in both precision medicine and biomanufacturing.” Udo J. Vetter, Founder and Managing Director of UV-Cap added: “We are excited to be able to support the long term aspiration of the team at the new Navigo Proteins. Their established technologies hold great potential to add substantial value to the growing fields of diagnostics, imaging and therapy in precision medicine as well as bioprocessing, helping to expand therapeutic pipelines and accelerate product development.” Brian Hunter, Managing Director of BioNet Ventures commented: “We are confident that UV-Cap’s backing will accelerate and strengthen Navigo Proteins’ future development, providing an environment for enhanced growth and ensuring continuity. We are pleased that the management and team will continue to be focused on collaborations with industrial partners from the bioprocessing, targeted imaging and therapy and the precision diagnostics industries.”

Garching, Germany and Halle, Germany – 24 March 2016 – ITM Isotopen Technologien München AG (ITM), a specialized radiopharmaceutical company, and Scil Proteins, the expert company in Affilin®-based protein engineering, today announced they have entered into a partnership covering the field of targeted radio conjugates. Under the terms of the agreement the partners plan to cover a number of programs for the discovery and development of novel targeted radio conjugates for imaging and therapy purposes, in a variety of indications. Scil Proteins will be responsible for the discovery and design of the radio conjugates based on its proprietary Affilin® platform, while ITM will use its radioisotope technology and be responsible for later-stage development and commercialization of the resulting products. The first program has commenced in the area of targeted cancer treatment. Henning Afflerbach, CEO of Scil Proteins commented: “ITM has outstanding capabilities and deep expertise in targeted radionuclide imaging and radionuclide therapy and this collaboration reinforces our leadership in the generation of targeted carriers as homogenous products specifically tailored to imaging and therapy applications.” “We have been impressed by the potential of Scil’s platform to deliver compounds with precisely engineered carriers”, added Steffen Schuster, CEO of ITM. “This enables us to select the compounds half-lives, short-term for imaging applications and longer-term for therapeutic applications – a perfect fit to our precision oncology strategy.” Affilin®-based biomolecules are derived from human scaffold proteins and have high stability, affinity and specificity making them ideal for a range of applications, including those where antibodies have limitations, thus broadening the potential of biotherapeutics.