100 Clinical Results associated with Northlake Gastroenterology Associates, L L P
0 Patents (Medical) associated with Northlake Gastroenterology Associates, L L P
Two Pediatric Cases Within a Familial Cluster and Hereditary Diffuse Gastric Carcinoma: A Tale of 2 Sisters
Author: Falgout, Lacey ; Gensler, Lawrence L.
ABSTRACTHereditary diffuse gastric cancer is a familial form of poorly differentiated signet ring cell carcinoma (SRCC) caused by a mutation in the CDH1/E-cadherin gene-mediating cell adhesion. CDH1 mutations are inherited in an autosomal dominant fashion and exhibit a high level of penetrance. SRCC diagnosis is exceedingly rare in the pediatric population. We report a case of SRCC in 2 sisters (10 and 15 years) and their father (41 years).
100 Deals associated with Northlake Gastroenterology Associates, L L P
100 Translational Medicine associated with Northlake Gastroenterology Associates, L L P