Delving into the Latest Updates on SYNLAB Unsecured Bondco Plc with Synapse

Overview

Author: Skov, Robert ; Coombs, Geoffrey ; Schaumburg, Frieder ; Alabi, Abraham ; Akpaka, Patrick Eberechi ; Peters, Georg ; Mellmann, Alexander ; Egyir, Beverly ; Laurent, Frederic ; Stegger, Marc ; Strommenger, Birgit ; Vandenesch, François ; Monecke, Stefan ; Breurec, Sebastien ; Strauß, Lena ; Larsen, Anders Rhod

Significance USA300 is a hypervirulent, community-acquired, multidrug-resistant Staphylococcus aureus clone that started to spread in the United States around 17 years ago. Many studies detected it also in South America, Europe, and the Asia-Pacific region. In this study, we show that USA300 is also circulating in sub-Saharan Africa. Locating the temporal and spatial origin of clonal lineages is important with respect to epidemiology and molecular evolution of pathogens. We show that USA300 evolved from a less virulent and less resistant ancestor circulating in Central Europe around 160 years ago. Constant surveillance of pathogen transmission routes is vital to prevent and control potential outbreaks. Whole genome sequencing proved to be a useful tool for epidemiological surveillance.

100 Deals associated with SYNLAB Unsecured Bondco Plc

Login to view more data

100 Translational Medicine associated with SYNLAB Unsecured Bondco Plc

Login to view more data