Last update 08 May 2025

Cardiokine Biopharma LLC

Subsidiary Company|Pennsylvania, United States

Overview

Related

1
Drugs associated with Cardiokine Biopharma LLC
Lixivaptan
Target
AVPR2
Mechanism
AVPR2 antagonists
Active Org.-
Originator Org.
Pfizer Inc.Pfizer Inc.
Active Indication-
Inactive Indication
Chronic hyponatremia [+4]
Drug Highest PhaseDiscontinued
First Approval Ctry. / Loc.-
First Approval Date-
9
Clinical Trials associated with Cardiokine Biopharma LLC
NCT01056848
/ CompletedNot Applicable
International, Multicenter Study of a Twenty-eight Week, Open-label, Titrated Oral Lixivaptan Administration in Patients With Chronic Hyponatremia: Extension to Studies CK-LX3401, 3405, and 3430
NCT01055912
/ CompletedPhase 2
Multicenter, Randomized, Double-Blind, Placebo- Controlled, Parallel Group, Efficacy and Safety Study to Evaluate the Effects of Oral Administration of Lixivaptan in Patients With Congestive Heart Failure
NCT00876876
/ WithdrawnPhase 3
International, Multicenter, Open-Label and Randomized Withdrawal Study of Oral Lixivaptan in Heart Failure Patients With Chronic Hyponatremia
100 Clinical Results associated with Cardiokine Biopharma LLC
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0 Patents (Medical) associated with Cardiokine Biopharma LLC
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100 Deals associated with Cardiokine Biopharma LLC
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100 Translational Medicine associated with Cardiokine Biopharma LLC
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Pipeline

Pipeline Snapshot as of 07 Mar 2026

The statistics for drugs in the Pipeline is the current organization and its subsidiaries are counted as organizations,Early Phase 1 is incorporated into Phase 1, Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3
Other
1
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Current Projects

Drug(Targets)IndicationsGlobal Highest Phase
Lixivaptan
 ( AVPR2 )		Heart Failure
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Pending
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Profit

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